Density of Con A receptors on T cell of bat and its implication on delayed activation

Abstract

The number of Con A receptor sites on T cell surface of bat lymphocyte was measured by using tritium-labelled Concanavalin A (3H-Con A). It was found that the average number of Con A receptor sites on a bat T cell is 3.6 X 10 +- 0.45 X 10. This value is significantly low compared to 10 Con A receptors on a murine lymphocyte and on a rat lymph node cells implication of this low density of Con A receotors on bat T cells in delayed activation of the lymphocytes in terms of blastogenesis and DNA synthesis is discussed.