ANTIBIOTIC PRINCIPLE FROM MORINGAE PTERYGOSPERMA - Part I. Purification

P A KURUP, P L NARASIMHA RAO

Abstract


1. Various methods of extraction of the antibiotic principle from the roots of Moringa pterygosperma have been investigated. Chromatographic method for its purification, studies on the adsorption and elution of the antibiotic on acid washed activated charcoal preparations are reported.

2. The "remarkable occurrence of free sulphur as an Impnrity in crude Pterygospermin preparations is reported.

3. Two fractions showing a potency of I in 600,000 when assayed against Micrococcus pyogenes var. aureus have been obtained by careful fractionation in hlgh vacuum.


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