STUDIES ON THE ANTIMICROBIAL ACTIVITY AND PHARMACOLOGICAL PROPERTIES OF SOME ESSENTIAL OILS, EXTRACTED FROM LOCALLY CULTIVATED PLANTS

M SIRSI, LEELA KALE, S NATARAJAN, U B NAYAK

Abstract


The essential oils from some plants of medicinal value are investigated for their tuberculostatic properties and antibacterial action.

The toxicity against a ciliated protozoa and the degree of irritation produced on rabbit's skin is determined.

The essential oil from Ocimum gratissimum which exhibited marked antitubercular and antibacterial activity with a low degree of irritability has been subjected for further pharmacological study.

This oil in a concentration of is found to inhibit the movements and relax the intestinal and uterine musculature; the oil antagonises the activity exhibited by barium chloride on intestinal movements.

The empirical use of this oil in conditions as ear-ache, tooth-ache, and abdominal colic in children can probably be explained by the local anresthetic action and the relaxation of the musculature produced by the essential oil.


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