BIOCHEMICAL BASIS To BLOCK ISCHAEMIA DEVELOPING INTO MYOCARDIAL INFARCTION : A SHORT REVIEW.

L M SRIVASTAVA, P K GANGULY

Abstract


The altered myocardial metabolism after an ischaemia is one of the recently recognized fields of interest. The molecular events involved from ischaemia to cell necrosis are still very controversial although, it seems that the overall metabolic changes have profound ill-effects on myocardium. It has also become apparent that if one could effectively reduce tissue damage following isch.aemia, its overall consequences might be averted. Many potential therapies designed to protect the ischaernic heart improve energy metabolism through changes in metabolic pathways. This article reviews some of the latest experimental findings and summarizes the present knowledge concerning biochemical basis of prevention of cellular injury in clinical and experimental myocardial infarction.

Keywords


Myocardial metabolism, myocardial infarction, energy metabolism, potential therapies.

Full Text:

PDF

Refbacks

  • There are currently no refbacks.