Chromosome behaviour during meiosis

Abstract

Pairing of homologous chromosomes and genetic recombination are key features of meiosis. DNA repair events at the pachytene interval of mammalian germ cells is very distinct and are often linked to the genetic recombination processes. The DNA polymorphism observed could be generated by the meiotic recombination-associated events. During the last few years our laboratory has been studying some of the aspects of DNA repair processes that occur in rat pachytene spermatocytes and also the behaviour of lamina structure during spermatogenesis. Some of our salient findings have been discussed here