Emerging applications of asymmetric dihydroxylation chemistry

Y Jayamma, E Nandanan, B B Lohray

Abstract


Applications of recently discovered asymmetric dihydroxylation (ADH) of alkenes in synthetic organic chemistry have been described. ADH reaction has been successfully implemented in the synthesis of several natural products, drugs and drug intermediates. It has also been utillzed in kinetic resolution and double diastereoselections in a few cases.

Keywords


ADH; oxidation; unfunctionalized alkenes; diols.

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